High Performance Center-Wide Heterogeneous Coupling Computing with WaitIO In this presentation, we will introduce h3-Open-SYS/WaitIO (abbreviated as WaitIO), a high-performance communication library that connects multiple MPI programs for heterogeneous coupled computing. WaitIO provides an inter-program communication environment between MPI programs and supports different MPI libraries corresponding to various interconnects and processor types. In this presentation, we will introduce the history of WaitIO development and examples of its application in related projects, including the JSC Collaboration Project and the JHPC-quantum Project. In the JHPC-quantum Project, we will also discuss the current development status of WaitIO-Router, which realizes center-wide communication among multiple systems, including the Quantum Computer on a wide-area network connected by SINET6.